CAF Champions League
FIFA Region
CAF
Season
2020-2021
Location
Africa
Abbreviation
CAFCL
Summary
The 2020-2021 CAF Champions League (CAFCL) is Africa's premier club football tournament where the top club teams from 42 of the 56 CAF F/As (football associations) are represented. (The F/As not represented are Cape Verde Islands, Central African Republic, Eritrea, Guinea-Bissau, Liberia, Madagascar, Malawi, Mauritius, Nambia, Réunion, São Tomé and Principe, Seychelles, Sierra Leone, and South Sudan.) The 2020-2021 winner will play against the 2020-2021 CAF Confederation Cup (CAFCC) winner in the 2020 CAF Super Cup. The top three 2020-2021 CAFCL teams will play in the 2021 FIFA World Cup in China.
Club teams qualified for the 2020-2021 CAFCL based on the Rankings for 2020-2021 CAF Competitions table. This table is based on results from each CAF Champions League and Confederation Cup from 2016 to 2019-2020 seasons. F/As that were not ranked (due to lack of results in previous CAFCL and CAFCC competitions) were only given one CAFCC berth.
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Rankings for 2020-2021 CAF Competitions
| F/A | CAF Rank | CAFCL Teams | CAFCC Teams |
|---|
| Morocco | 1 | 2 | 2 |
| Egypt | 2 | 2 | 2 |
| Tunisia | 3 | 2 | 2 |
| Congo DR | 4 | 2 | 2 |
| Algeria | 5 | 2 | 2 |
| South Africa | 6 | 2 | 2 |
| Zambia | 7 | 2 | 2 |
| Nigeria | 8 | 2 | 2 |
| Guinea | 9 | 2 | 2 |
| Angola | 10 | 2 | 2 |
| Sudan | 11 | 2 | 2 |
| Libya | 12 | 2 | 2 |
| Tanzania | 13 | 1 | 1 |
| Côte d'Ivoire | 14 | 1 | 1 |
| Kenya | 15 | 1 | 1 |
| Zimbabwe | 15 | 1 | 1 |
| Mozambique | 17 | 1 | 1 |
| Congo | 18 | 1 | 1 |
| Uganda | 18 | 1 | 1 |
| Ghana | 20 | 1 | 1 |
| Mali | 20 | 1 | 1 |
| Madagascar | 21 | 1 | 1 |
| Rwanda | 22 | 1 | 1 |
| Eswatini | 23 | 1 | 1 |
| Ethiopia | 24 | 1 | 1 |
| Botswana | 25 | 1 | 1 |
| Togo | 25 | 1 | 1 |
| Benin | 27 | 1 | 1 |
| Mauritania | 27 | 1 | 1 |
| Burkina Faso | 29 | 1 | 1 |
| Cameroon | 29 | 1 | 1 |
| Gabon | 31 | 1 | 1 |
Competition Structure
| Stage | # Teams | New Teams Entering This Round | Teams From Previous Round | Format |
|---|---|---|---|---|
| Premliminary Round | 44 | 44 | 22 sets of Home/Away matches, highest aggregate goals advances | |
| First Round | 32 | 10 clubs that received Preliminary Round byes | 22 winners from Preliminary Round | 16 sets of Home/Away matches, highest aggregate goals advances |
| Group Stage | 16 | None | 16 winners from First Round | 4 groups of 4 with Home/Away matches against each team in group, top 2 teams with most points (win = 3 pts, draw = 1 pt) in each group advance |
| Quarterfinals | 8 | None | top 2 teams with most points from each group in Group stage | 4 sets of Home/Away matches, highest aggregate goals advances |
| Semifinals | 4 | None | 4 winners from Quarterfinals | 2 sets of Home/Away matches, highest aggregate goals advances |
| Finals | 2 | None | 2 winners from Semifinals | Home/Away matches, highest aggregate goals advances |
Group
| Group A | League | Home | Road | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| POS | MP | W - D - L | PTS | CPTS | GF | GA | GD | MP | W - D - L | PTS | GF | GA | GD | MP | W - D - L | PTS | GF | GA | GD | |
| 1 | Al-Ahli SC | 0 | 0 -0-0 | 0 | - | 0 | 0 | 0 | 0 | 0 -0-0 | 0 | 0 | 0 | 0 | 0 | 0 -0-0 | 0 | 0 | 0 | 0 |
| 2 | Al-Merreikh SC | 0 | 0 -0-0 | 0 | - | 0 | 0 | 0 | 0 | 0 -0-0 | 0 | 0 | 0 | 0 | 0 | 0 -0-0 | 0 | 0 | 0 | 0 |
| 3 | AS Vita Club | 0 | 0 -0-0 | 0 | - | 0 | 0 | 0 | 0 | 0 -0-0 | 0 | 0 | 0 | 0 | 0 | 0 -0-0 | 0 | 0 | 0 | 0 |
| 4 | Simba SC | 0 | 0 -0-0 | 0 | - | 0 | 0 | 0 | 0 | 0 -0-0 | 0 | 0 | 0 | 0 | 0 | 0 -0-0 | 0 | 0 | 0 | 0 |
Quarterfinals | ||||||||||||||||||||
| Date | Home | Status | Road | Venue | ||||
| 11.02.21 |  | Simba SC (TAN1) | Stade Tata Raphaël |
 | Al-Merreikh SC (SDN1) | Petra Stadium |
| 22.02.21 | | AS Vita Club (COD1) | Stade de Al-Merrikh |
| Al-Ahli SC (JOR1) | Benjamin Mkapa National Stadium |
| 04.03.21 | | Simba SC (TAN1) | Stade de Al-Merrikh |
| AS Vita Club (COD1) | Petra Stadium |
| 15.03.21 | | Al-Merreikh SC (SDN1) | Benjamin Mkapa National Stadium |
| Al-Ahli SC (JOR1) | Stade Tata Raphaël |
| 01.04.21 | | AS Vita Club (COD1) | Benjamin Mkapa National Stadium |
| Al-Ahli SC (JOR1) | Stade de Al-Merrikh |
| 08.04.21 | | Simba SC (TAN1) | Petra Stadium |
| Al-Merreikh SC (SDN1) | Stade Tata Raphaël |
| Group B | League | Home | Road | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| POS | MP | W - D - L | PTS | CPTS | GF | GA | GD | MP | W - D - L | PTS | GF | GA | GD | MP | W - D - L | PTS | GF | GA | GD | |
| 1 | Al-Hilal FC | 0 | 0 -0-0 | 0 | - | 0 | 0 | 0 | 0 | 0 -0-0 | 0 | 0 | 0 | 0 | 0 | 0 -0-0 | 0 | 0 | 0 | 0 |
| 2 | CR Belouizdad | 0 | 0 -0-0 | 0 | - | 0 | 0 | 0 | 0 | 0 -0-0 | 0 | 0 | 0 | 0 | 0 | 0 -0-0 | 0 | 0 | 0 | 0 |
| 3 | Mamelodi Sundowns FC | 0 | 0 -0-0 | 0 | - | 0 | 0 | 0 | 0 | 0 -0-0 | 0 | 0 | 0 | 0 | 0 | 0 -0-0 | 0 | 0 | 0 | 0 |
| 4 | TP Mazembe | 0 | 0 -0-0 | 0 | - | 0 | 0 | 0 | 0 | 0 -0-0 | 0 | 0 | 0 | 0 | 0 | 0 -0-0 | 0 | 0 | 0 | 0 |
Quarterfinals | ||||||||||||||||||||
| Date | Home | Status | Road | Venue | ||||
| 11.02.21 |  | CR Belouizdad (ALG1) | Stade du TP Mazembe |
 | Al-Hilal FC (SDN1) | Loftus Versfeld Stadium |
| 22.02.21 | | TP Mazembe (COD1) | Al-Hilal Stadium |
| Mamelodi Sundowns FC (RSA1) | Stade du 20 Août 1955 (Algiers) |
| 04.03.21 | | Al-Hilal FC (SDN1) | Stade du 20 Août 1955 (Algiers) |
| Mamelodi Sundowns FC (RSA1) | Stade du TP Mazembe |
| 15.03.21 | | CR Belouizdad (ALG1) | Al-Hilal Stadium |
| TP Mazembe (COD1) | Loftus Versfeld Stadium |
| 01.04.21 | | Mamelodi Sundowns FC (RSA1) | Al-Hilal Stadium |
| TP Mazembe (COD1) | Stade du 20 Août 1955 (Algiers) |
| 08.04.21 | | Al-Hilal FC (SDN1) | Stade du TP Mazembe |
| CR Belouizdad (ALG1) | Loftus Versfeld Stadium |
| Group C | League | Home | Road | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| POS | MP | W - D - L | PTS | CPTS | GF | GA | GD | MP | W - D - L | PTS | GF | GA | GD | MP | W - D - L | PTS | GF | GA | GD | |
| 1 | Horoya AC | 0 | 0 -0-0 | 0 | - | 0 | 0 | 0 | 0 | 0 -0-0 | 0 | 0 | 0 | 0 | 0 | 0 -0-0 | 0 | 0 | 0 | 0 |
| 2 | Kaizer Chiefs FC | 0 | 0 -0-0 | 0 | - | 0 | 0 | 0 | 0 | 0 -0-0 | 0 | 0 | 0 | 0 | 0 | 0 -0-0 | 0 | 0 | 0 | 0 |
| 3 | Petróleos Luanda | 0 | 0 -0-0 | 0 | - | 0 | 0 | 0 | 0 | 0 -0-0 | 0 | 0 | 0 | 0 | 0 | 0 -0-0 | 0 | 0 | 0 | 0 |
| 4 | Wydad Casablanca | 0 | 0 -0-0 | 0 | - | 0 | 0 | 0 | 0 | 0 -0-0 | 0 | 0 | 0 | 0 | 0 | 0 -0-0 | 0 | 0 | 0 | 0 |
Quarterfinals | ||||||||||||||||||||
| Date | Home | Status | Road | Venue | ||||
| 11.02.21 |  | Kaizer Chiefs FC (RSA1) | Stade Mohamed V |
 | Petróleos Luanda (ANG1) | Stade du 28 Septembre |
| 22.02.21 | | Wydad Casablanca (MAR1) | Estádio 11 de Novembro |
| Horoya AC (GUI1) | FNB Stadium (Soccer City) |
| 04.03.21 | | Petróleos Luanda (ANG1) | FNB Stadium (Soccer City) |
| Horoya AC (GUI1) | Stade Mohamed V |
| 15.03.21 | | Kaizer Chiefs FC (RSA1) | Estádio 11 de Novembro |
| Wydad Casablanca (MAR1) | Stade du 28 Septembre |
| 01.04.21 | | Horoya AC (GUI1) | Estádio 11 de Novembro |
| Wydad Casablanca (MAR1) | FNB Stadium (Soccer City) |
| 08.04.21 | | Petróleos Luanda (ANG1) | Stade Mohamed V |
| Kaizer Chiefs FC (RSA1) | Stade du 28 Septembre |
| Group D | League | Home | Road | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| POS | MP | W - D - L | PTS | CPTS | GF | GA | GD | MP | W - D - L | PTS | GF | GA | GD | MP | W - D - L | PTS | GF | GA | GD | |
| 1 | ES de Tunis | 0 | 0 -0-0 | 0 | - | 0 | 0 | 0 | 0 | 0 -0-0 | 0 | 0 | 0 | 0 | 0 | 0 -0-0 | 0 | 0 | 0 | 0 |
| 2 | MC Alger | 0 | 0 -0-0 | 0 | - | 0 | 0 | 0 | 0 | 0 -0-0 | 0 | 0 | 0 | 0 | 0 | 0 -0-0 | 0 | 0 | 0 | 0 |
| 3 | Teungueth FC | 0 | 0 -0-0 | 0 | - | 0 | 0 | 0 | 0 | 0 -0-0 | 0 | 0 | 0 | 0 | 0 | 0 -0-0 | 0 | 0 | 0 | 0 |
| 4 | Zamalek SC | 0 | 0 -0-0 | 0 | - | 0 | 0 | 0 | 0 | 0 -0-0 | 0 | 0 | 0 | 0 | 0 | 0 -0-0 | 0 | 0 | 0 | 0 |
Quarterfinals | ||||||||||||||||||||
| Date | Home | Status | Road | Venue | ||||
| 11.02.21 |  | MC Alger (ALG1) | Cairo International Stadium |
 | Teungueth FC (SEN1) | Stade Olympique de Radès |
| 22.02.21 | | ES de Tunis (TUN1) | Stade Omar Hamadi de Bologhine |
| Zamalek SC (EGY1) | Stade Amadou Barry |
| 04.03.21 | | MC Alger (ALG1) | Stade Amadou Barry |
| Zamalek SC (EGY1) | Stade Olympique de Radès |
| 15.03.21 | | Teungueth FC (SEN1) | Stade Omar Hamadi de Bologhine |
| ES de Tunis (TUN1) | Cairo International Stadium |
| 01.04.21 | | Zamalek SC (EGY1) | Stade Omar Hamadi de Bologhine |
| ES de Tunis (TUN1) | Stade Amadou Barry |
| 08.04.21 | | MC Alger (ALG1) | Stade Olympique de Radès |
| Teungueth FC (SEN1) | Cairo International Stadium |
1st Round
| Date | Home | Status | Road | Venue | ||||
| Aggregate | Young Buffaloes FC (SWZ1) | 36 | AS Vita Club (COD1) |
| 22.12.20 |  | 22 | AS Vita Club (COD1) | Mavuso Sports Centre |
| 06.01.21 | | 41 | Young Buffaloes FC (SWZ1) | Stade des Martyrs |
| Aggregate | Jwaneng Galaxy FC (BOT1) | 15 | Mamelodi Sundowns FC (RSA1) |
| 22.12.20 |  | 02 | Mamelodi Sundowns FC (RSA1) | Lobatse Stadium |
| 05.01.21 | | 31 | Jwaneng Galaxy FC (BOT1) | Loftus Versfeld Stadium |
| Aggregate | Teungueth FC (SEN1) | 00 | Raja Casablanca (MAR1) |
| 22.12.20 | | 00 | Raja Casablanca (MAR1) | Stade Lat Dior |
| 05.01.21 | | 00 | Teungueth FC (SEN1) | Stade Mohamed V | ||
| Teungueth FC advances on PKs (3-1) | ||||||
| Aggregate | Gazelle FC (CHA1) | 04 | Zamalek SC (EGY1) |
| 23.12.20 |  | 02 | Zamalek SC (EGY1) | Petrosport Stadium | ||
| Match awarded 2-0 to Zamalak SC by walkover. | ||||||
| 05.01.21 | | 20 | Gazelle FC (CHA1) | Cairo International Stadium | ||
| Match awarded 2-0 to Zamalak SC by walkover. | ||||||
| Aggregate | Al-Merreikh SC (SDN1) | 42 | Enyimba International (NGA1) |
| 23.12.20 | | 30 | Enyimba International (NGA1) | Al-Hilal Stadium |
| 06.01.21 | | 21 | Al-Merreikh SC (SDN1) | Enyimba International Stadium |
| Aggregate | Nkana FC (ZAM1) | 01 | Petróleos Luanda (ANG1) |
| 23.12.20 |  | 00 | Petróleos Luanda (ANG1) | Nkana Stadium |
| 06.01.21 | | 10 | Nkana FC (ZAM1) | Estádio 11 de Novembro |
| Aggregate | FC Platinum (ZIM1) | 14 | Simba SC (TAN1) |
| 23.12.20 |  | 10 | Simba SC (TAN1) | National Sports Stadium (Harare) |
| 06.01.21 | | 40 | FC Platinum (ZIM1) | Benjamin Mkapa National Stadium |
| Aggregate | AS SONIDEP (NIG1) | 05 | Al-Ahli SC (JOR1) |
| 23.12.20 |  | 01 | Al-Ahli SC (JOR1) | Général Seyni Kountché Stadion |
| 05.01.21 | | 40 | AS SONIDEP (NIG1) | All Ahly WE Al Salam Stadium |
| Aggregate | Bouenguidi FC (GAB1) | 24 | TP Mazembe (COD1) |
| 23.12.20 |  | 12 | TP Mazembe (COD1) | Stade Augustin Monédan de Sibang |
| 06.01.21 | | 21 | Bouenguidi FC (GAB1) | Stade TP Mazembe |
| Aggregate | Asante Kotoko SC (GHA1) | 03 | Al-Hilal FC (SDN1) |
| 23.12.20 |  | 01 | Al-Hilal FC (SDN1) | Ohene Djan Sports Stadium (Accra) |
| 06.01.21 | | 20 | Asante Kotoko SC (GHA1) | Al-Hilal Stadium | ||
| Match awarded 2-0 to Al-Hilal FC by walkover | ||||||
| Aggregate | Stade Malien de Bamako (MLI1) | 13 | Wydad Casablanca (MAR1) |
| 23.12.20 |  | 10 | Wydad Casablanca (MAR1) | Stade du 26 Mars |
| 06.01.21 | | 30 | Stade Malien de Bamako (MLI1) | Stade Mohamed V |
| Aggregate | Racing Club d'Abidjan (CIV1) | 12 | Horoya AC (GUI1) |
| 23.12.20 |  | 11 | Horoya AC (GUI1) | Stade Olympique Alassane Ouattara |
| 06.01.21 | | 10 | Racing Club d'Abidjan (CIV1) | Stade du 28 Septembre |
| Aggregate | Al-Ahly SC Benghazi (LBY1) | 23 | ES de Tunis (TUN1) |
| 23.12.20 |  | 00 | ES de Tunis (TUN1) | Petrosport Stadium |
| 06.01.21 | | 32 | Al-Ahly SC Benghazi (LBY1) | Stade Olympique de Radès |
| Aggregate | Kaizer Chiefs FC (RSA1) | 10 | CD 1º de Agosto (ANG1) |
| 23.12.20 | | 00 | CD 1º de Agosto (ANG1) | FNB Stadium (Soccer City) |
| 05.01.21 | | 01 | Kaizer Chiefs FC (RSA1) | Estádio 11 de Novembro |
| Aggregate | CR Belouizdad (ALG1) | 81 | Gor Mahia FC (KEN1) |
| 26.12.20 | | 60 | Gor Mahia FC (KEN1) | Stade 5 Juillet 1962 |
| 06.01.21 | | 12 | CR Belouizdad (ALG1) | Nyayo National Stadium |
| Aggregate | MC Alger (ALG1) | 21 | CS Sfaxien (TUN1) |
| 28.12.20 | | 20 | CS Sfaxien (TUN1) | Stade 5 Juillet 1962 |
| 06.01.21 | | 10 | MC Alger (ALG1) | Stade Taïeb Mhiri |
Preliminary Round
| Date | Home | Status | Road | Venue | ||||
| Aggregate | Forest Rangers FC (ZAM1) | 02 | Bouenguidi FC (GAB1) |
| 28.11.20 |  | 00 | Bouenguidi FC (GAB1) | Levy Mwanawasa Stadium |
| 05.12.20 | | 20 | Forest Rangers FC (ZAM1) | Stade Augustin Monédan de Sibang |
| Aggregate | APR FC (RWA1) | 34 | Gor Mahia FC (KEN1) |
| 28.11.20 |  | 21 | Gor Mahia FC (KEN1) | Stade Régional de Nyamirambo |
| 05.12.20 | | 31 | APR FC (RWA1) | Nyayo National Stadium |
| Aggregate | Young Buffaloes FC (SWZ1) | 11 | Le Messager FC (BDI1) |
| 28.11.20 | | 00 | Le Messager FC (BDI1) | Mavuso Sports Centre |
| 06.12.20 | | 11 | Young Buffaloes FC (SWZ1) | Stade Urukundo | ||
| Young Buffaloes FC advances w/more away goals (1-0) | ||||||
| Aggregate | Vipers SC (UGA1) | 02 | Al-Hilal FC (SDN1) |
| 28.11.20 |  | 01 | Al-Hilal FC (SDN1) | St. Mary's Stadium (Kitende) |
| 06.12.20 | | 10 | Vipers SC (UGA1) | Al-Hilal Stadium |
| Aggregate | Jwaneng Galaxy FC (BOT1) | 51 | US Zilimadjou (COM1) |
| 28.11.20 | | 40 | US Zilimadjou (COM1) | Lobatse Stadium |
| 06.12.20 | | 11 | Jwaneng Galaxy FC (BOT1) | Stade de Moroni |
| Aggregate | CD Costa do Sol (MOZ1) | 14 | FC Platinum (ZIM1) |
| 28.11.20 |  | 12 | FC Platinum (ZIM1) | Estádio do Zimpeto |
| 05.12.20 | | 20 | CD Costa do Sol (MOZ1) | National Sports Stadium (Harare) |
| Aggregate | Buffles de Borgou FC (BEN1) | 14 | MC Alger (ALG1) |
| 28.11.20 |  | 11 | MC Alger (ALG1) | Stade Charles de Gaulle (Porto-Novo) |
| 04.12.20 | | 30 | Buffles de Borgou FC (BEN1) | Stade 5 Juillet 1962 | ||
| Match awarded 2-0 to MC Alger by walkover | ||||||
| Aggregate | Mlandege FC (ZAN1) | 18 | CS Sfaxien (TUN1) |
| 28.11.20 |  | 05 | CS Sfaxien (TUN1) | Amaan Stadium (Zanzibar City) |
| 05.12.20 | | 31 | Mlandege FC (ZAN1) | Stade Taïeb Mhiri |
| Aggregate | Al-Ahly SC Benghazi (LBY1) | 60 | Mekelle 70 Enderta FC (ETH1) |
| 28.11.20 | | 30 | Mekelle 70 Enderta FC (ETH1) | Petrosport Stadium | ||
| Match awarded 2-0 to Al-Ahly SC Benghazi by walkover | ||||||
| 05.12.20 | | 03 | Al-Ahly SC Benghazi (LBY1) | Addis Ababa National Stadium | ||
| Match awarded 2-0 to Al-Ahly SC Benghazi by walkover | ||||||
| Aggregate | PWD Bamenda (CMR1) | 01 | Kaizer Chiefs FC (RSA1) |
| 29.11.20 |  | 01 | Kaizer Chiefs FC (RSA1) | Limbé Omnisport Stadium |
| 05.12.20 | | 00 | PWD Bamenda (CMR1) | FNB Stadium (Soccer City) |
| Aggregate | Bantu FC (LES1) | 01 | Nkana FC (ZAM1) |
| Aggregate | Ashanti Golden Boys (GUI1) | 15 | Stade Malien de Bamako (MLI1) |
| 29.11.20 |  | 12 | Stade Malien de Bamako (MLI1) | Stade du 28 Septembre |
| 05.12.20 | | 30 | Ashanti Golden Boys (GUI1) | Stade du 26 Mars | ||
| Match awarded 2-0 to Stade Malien de Bamako by walkover | ||||||
| Aggregate | AS Otôho d'Oyo (CGO1) | 13 | Al-Merreikh SC (SDN1) |
| 29.11.20 |  | 11 | Al-Merreikh SC (SDN1) | Stade Omnisport Marien Ngouabi d'Owando |
| 04.12.20 | | 20 | AS Otôho d'Oyo (CGO1) | Al-Hilal Stadium |
| Aggregate | Akonangui FC (EQG1) | 23 | Petróleos Luanda (ANG1) |
| 29.11.20 |  | 01 | Petróleos Luanda (ANG1) | Nuevo Estadio de Ebebiyín |
| 05.12.20 | | 22 | Akonangui FC (EQG1) | Estádio 11 de Novembro |
| Aggregate | Gazelle FC (CHA1) | 60 | Garde Républicaine / SIAF (DJI1) |
| 29.11.20 | | 30 | Garde Républicaine / SIAF (DJI1) | Stade Omnisports Idriss Mahamat Ouya | ||
| Match awarded 2-0 to Gazelle FC by walkover | ||||||
| 04.12.20 | | 03 | Gazelle FC (CHA1) | Stade El Hadj Hassan Gouled | ||
| Match awarded 2-0 to Gazelle FC by walkover | ||||||
| Aggregate | Plateau United FC (NGA1) | 01 | Simba SC (TAN1) |
| 29.11.20 |  | 01 | Simba SC (TAN1) | Jos International Stadium |
| 05.12.20 | | 00 | Plateau United FC (NGA1) | Benjamin Mkapa National Stadium |
| Aggregate | Racing Club d'Abidjan (CIV1) | 22 | ASKO de Kara (TOG1) |
| 29.11.20 | | 10 | ASKO de Kara (TOG1) | Stade Olympique Alassane Ouattara |
| 06.12.20 | | 21 | Racing Club d'Abidjan (CIV1) | Stade de Kégué | ||
| Racing Club d'Abidjan advances w/more away goals (1-0) | ||||||
| Aggregate | AS SONIDEP (NIG1) | 20 | Mogadishu City Club (SOM1) |
| 29.11.20 | | 20 | Mogadishu City Club (SOM1) | Général Seyni Kountché Stadion |
| 05.12.20 | | 00 | AS SONIDEP (NIG1) | Stade El Hadj Hassan Gouled |
| Aggregate | Rahimo FC (BFA1) | 12 | Enyimba International (NGA1) |
| 29.11.20 |  | 01 | Enyimba International (NGA1) | Stade du 4-Août |
| 06.12.20 | | 11 | Rahimo FC (BFA1) | Enyimba International Stadium |
| Aggregate | FC Nouadhibou (MTN1) | 11 | Asante Kotoko SC (GHA1) |
| 29.11.20 |  | 11 | Asante Kotoko SC (GHA1) | Stade Municipal de Nouadhibou |
| 06.12.20 | | 00 | FC Nouadhibou (MTN1) | Ohene Djan Sports Stadium (Accra) | ||
| Asante Kotoko SC advances w/more away goals (1-0) | ||||||
| Aggregate | CR Belouizdad (ALG1) | 40 | Al-Nasr Club (LBY1) |
| 29.11.20 | | 20 | Al-Nasr Club (LBY1) | Stade 5 Juillet 1962 |
| 06.12.20 | | 02 | CR Belouizdad (ALG1) | Petrosport Stadium |
| Aggregate | Armed Forces FC (GAM1) | 13 | Teungueth FC (SEN1) |
| 29.11.20 |  | 11 | Teungueth FC (SEN1) | Independence Stadium (Bakau) |
| 06.12.20 | | 20 | Armed Forces FC (GAM1) | Stade Lat Dior |